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doi: 10.3390/antiox13020197, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 224
It proved to decrease the time to return to sports among the group who did PRP injection with physiotherapy compared to the control group that underwent rehabilitation alone
The study by Armagan et al
Other RA prevention trials such as the TREAT Early Arthralgia to Reverse or Limit Impending Exacerbation to Rheumatoid arthritis (TREAT EARLIER) trial examining one year of methotrexate also did not meet its endpoint of development of clinical arthritis among individuals with arthralgia clinically suspected of progressing to RA and magnetic resonance imaging (MRI)-detected subclinical joint inflammation (183)

Plasma levels decline significantly: approximately 200 ng/ml at age 20, dropping to roughly 80 ng/ml by age 60