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Two-dimensional Ca2Mn8O16 nanosheets mimic enzyme activities, generate ROS, and induce Ca2 + overload, amplifying the synergistic effects of ferroptosis and apoptosis [117]

[PubMed] [Google Scholar] Battersby IA, Giger U, Hall EJ

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The released DC_AC50 can promote significant intracellular accumulation of cisplatin and copper by inhibiting the ATOX1-ATPase pathway, thereby enhancing the chemotherapeutic effect of cisplatin and inducing significant ROS production