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The relationship between vitamin B12 supplementation and acne development has been a subject of clinical interest and patient concern for several years
1 2 3 "Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation" (PDF)
In UK primary care, patients with a B12 above 1,000 pmol/L had a one-year cancer incidence rate ratio of 4.72 compared with those in the reference range

The staff was so kind throughout this process each time they showed me my before and after photos I almost came to tears, happy tears

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