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Specifically, an imbalance between oxidants and antioxidants, increased ROS production, a reduction in antioxidant enzymes function contribute to the pathogenesis and development of psoriasis [3]

These cytokines are required for a successful immune response, but excessive production can cause a cytokine storm, leading to widespread of inflammation and tissue damage [19]

data are reported as mean SEM

LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction

In earlier research, IL-1 release and activation through interleukin-converting enzyme (ICE) and caspase-1 may contribute to acute seizures and drug-resistant chronic epilepsy in mice (Maroso et al., 2011)