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Interestingly, NAC has been used in medicine for decades as a treatment for paracetamol overdose and is recognised by the WHO as an essential medicine

Vagal afferents detect mechanical stretch, nutrients, and microbial molecules in the gut, triggering brainstem nuclei that influence mood, appetite, and parasympathetic output

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It needs pharmacokinetic data

At the same time, drugs also have a certain degree of side effects, such as the development of drug resistance, as well as adverse reactions to gastrointestinal symptoms, neurological and psychiatric symptoms, and other systemic symptoms