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Subsequently, 1717 articles were excluded because they did not meet the inclusion criteria

The expression levels were compared between treated and control groups [2]

Comparison Section Q28: 5-Amino-1MQ vs Semaglutide Semaglutide: GLP-1 receptor agonist appetite suppression approved medication 5-Amino-1MQ: NNMT inhibitor metabolic enzyme target investigational compound Q29: 5-Amino-1MQ vs Tirzepatide Tirzepatide: dual incretin agonist clinically validated 5-Amino-1MQ: intracellular metabolic regulator early-stage research Q30: 5-Amino-1MQ vs NAD boosters NAD precursors aim to increase NAD availability directly

In addition, with the advancement of anti-aging research, the formulation of 5-amino-1mq capsules may be further optimized, such as developing sustained-release or targeted capsules to improve bioavailability and tissue targeting, better adapting to diverse research scenarios

NNMT and GLUT4 appear to be closely linked in these processes