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Intriguingly, the GABAergic dysregulations, a neurological hallmark of epilepsy and neuropsychiatric disorders [30, 31], can also impact the activity of the motor cortical network in MND, such as ALS [1, 5]

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Therefore, carnitine/acylcarnitine not only play roles in muscle energy metabolism but also participate in the whole-body energy balance and fatigue perception by affecting neuromuscular signaling, underscoring the potential importance of carnitine in exercise physiology, exercise recovery and performance improvement

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Association of thigh muscle mass with insulin resistance and incident type 2 diabetes mellitus in japanese americans