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Due to having the aforementioned pharmacological actions, acetyl L-carnitine is clinically used to treat depression associated with the primary degenerative disease (Alzheimer's Dementia), is also prescribed to treat the secondary degenerative disease (vascular dementia), and is a broad-spectrum agent which can be used as a first-selective drug ex hibiting excellent ameliorating effects on early- stage dementia patients (The Journal of Applied Pharmacology (2001) 9:285-290)

The results showed a significant improvement in lesions (erythema, vesicles, scaling) and a reduction in pruritus in the treated group

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Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress

doi: 10.1016/j.mam.2004.06.002