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Upon exposure to SARS-CoV-2, B cells that recognize viral antigens are activated, transit to germinal centres, undergo class-switch recombination and progress through iterative rounds of somatic hypermutation 10,11,12

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The focus will primarily be on interactions at the pharmacokinetic level, as they are more challenging to understand and predict, and the precise mechanisms have not been adequately explored or confirmed

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Thats whats changed. FDA-approved peptide drugs such as insulin and oxytocin have been available for decades
