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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.He Y.-F., Li B.-Z., Li Z., Liu P., Wang Y., Tang Q., Ding J., Jia Y., Chen Z., Li L., et al

Surg Endosc (2020) 35(5):2091103

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Emerging evidence suggests that disruptions to the early microbiomedue to antibiotic exposure, poor maternal diet, or lack of breastfeedingcan alter synaptic pruning, neurotransmitter systems, and stress reactivity in ways that may predispose individuals to cognitive deficits and mood disorders later in life

More importantly, type 2 diabetic iMyos show a large degree of perturbations in pathways outside of the canonical insulin signalling pathway and not regulated by insulin (Fig
