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J Biol Chem 286:88468856 Sricholpech M, Perdivara I, Yokoyama M, Nagaoka H, Terajima M, Tomer KB, Yamauchi M (2012) Lysyl hydroxylase 3-mediated glucosylation in type i collagen: molecular loci and biological significance

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The FDA looks for clear acceptance of responsibility and a collaborative, solution-oriented approach
Some suggest splitting doses, others insist on single morning administration
