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Congenital causes are rare and are the result of genetic mutations in genes encoding proteins involved in B12 absorption, transport, and intracellular processing

Starting at 1.0 mg significantly increases the risk of nausea, vomiting, and other gastrointestinal side effects
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147 Functionally, females produce stronger vaccine-induced antibody responses than males do, underscoring the need for sex-specific immunization strategies for elderly individuals
