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According to WHO criteria, population iodine deficiency is defined by median urinary iodine concentrations lower than 150 micrograms (g)/L for pregnant women and 100 g/L for all other groups ( Table 1 )

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For the sample with ajoene, the determined PrSMs modification mass was +68.9884 Da, which is lower than the expected value (+71.9995 Da) but could be due to the oxidation of cysteine residues, as observed during previous mass spectrometry measurements (Fig

Thus, these results indicated that the cohort of sporadic ALS patients had a deficiency of Gpx4 protein