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Description
Numerous studies demonstrated that this small molecule is crucial in many different human diseases such as aging, diabetes, acquired immune deficiency syndrome (AIDS), as well as neurodegenerative and liver diseases (30)

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Related molecular mechanism studies using immunohistochemistry and Western blot analysis revealed significantly decreased GPX4 protein levels and upregulated pro-ferroptotic proteins ACSL4 and p53 in the OA cartilage layer

Acta 719 , 2431 (1982) Graceffa P.: Arch