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However, azoles are less effective for aspergillosis or systemic yeast infections, and long-term use may result in hepatotoxicity, though they are generally better tolerated than polyenes ( ERG11 , reducing azole binding to the target enzyme (Lee et al., 2021)
Structure, function, and regulation of the blood-brain barrier tight junction in central nervous system disorders
This would render the DSIP ineffective for your research
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doi: 10.1038/s41598-018-36374-4 368 van ExelE.KoopmanJ
