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Hydroxocobalamin appears as dark red orthorhombic needles or as an amorphous or crystalline red powder

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Active B12 has a shorter circulating half-life compared to inactive B12, so the earliest change that occurs on entering negative B12 balance (low total-B12 levels) is likely to be a decrease in plasma active B12 (holoTC) concentration

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For this reason, obtaining professional support is essential