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They are indicated together with diet and physical activity in adults who have obesity (BMI of 30 kg/m2 or more) or overweight (BMI between 27 and 30 kg/m2) and have weight related health problems such as diabetes, abnormally high levels of fat in the blood, high blood pressure or obstructive sleep apnoea (frequent interruption of breathing during sleep)

doi: 10.1371/journal.pone.0178329 116 PrinzPStengelA

Novo Nordisk has announced the results of a trial of CagriSema for the treatment of stage 2 diabetes, which proved that CagriSema's hypoglycemic effect is better than that of semeglutide, and nearly 90% of subjects have achieved the HbA1c goal

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All authors took part in drafting, revising or critically reviewing the article