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Nanomaterials 13:2486 Wang Y, Peng X, Hu J et al (2021) Low-dose colchicine in type 2 diabetes with microalbuminuria: a double-blind randomized clinical trial

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Its primary mechanism involves NADPH oxidase system modulation and enhancement of the Nrf2 signalling pathway, which collectively reduce ROS generation and promote tissue regeneration

However, factors like aging, stress, pollution, and poor diet reduce its levels

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