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Retatrutide is still investigational and not approved by any regulator as of April 2026, so everything below is presented as clinical-trial data, not as medical guidance

If you're working with a lyophilized (freeze-dried) powder, proper reconstitution is critical
Waiting for diagnosis carries a high risk, while injecting B12 carries no risk

Furthermore, hypertension is a primary risk factor for chemotherapy-induced cardiotoxicity, one of the most severe cardiovascular adverse effects of anticancer treatments
It just makes the process miserable and increases the risk of discontinuation
