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Neuropathic pain can be peripheral, (outside the central nervous system), like carpal tunnel pain or central , originating in the spinal cord or brain

It takes years to develop the full-blown symptoms of pernicious anemia

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doi:10.1021/acsinfecdis.0c00288 Ghezzi P, Lemley KV, Andrus JP, De Rosa SC, Holmgren A, Jones D, Jahoor F, Kopke R, Cotgreave I, Bottiglieri T, Kaplowitz N, Nakamura H, Staal F, Ela SW, Atkuri KR, Tirouvanziam R, Heydari K, Sahaf B, Zolopa A, Frye RE, Mantovani JJ, Herzenberg LA, Herzenberg LA