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Also, after weight loss surgery, patients are on a very restricted diet and adjusting to a reduction in stomach capacity making it difficult to ingest all the nutritional supplements required

In order to improve outcomes, biphasic scaffolds can be created with a softer upper layer containing chondrogenic factors (e.g., TGF-, chondroitin sulfate) and a stiffer lower layer, often loaded with calcium phosphate, hydroxyapatite, or bone morphogenetic protein (BMP), to provide structural support of the above cartilage layer and to promote osteogenic tissue formation and boney integration

For example, a BMP-2 mimetic peptide known as P20 (KIPKASSVPTELSAISTLYL) was derived from the knuckle antigenic epitope, which represents the core functional region essential for osteogenesis [81]

endogeno al corpo umano, il che riduce la probabilit di risposte immunitarie

To clear things up, we