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[,] Evidence suggests that lycopene impedes the growth of PCa cells through the PPARLXR-ABCA1 pathway

Oxidative stress does not occur randomly it is driven upward by: undermethylation copper overload immune activation high sugar diets nutrient deficiencies sleep disruption physical or emotional stress environmental exposures When antioxidants are low, the brain cannot: regulate sensory input maintain mitochondrial energy detoxify inflammatory byproducts stabilize mood or attention manage stress hormones This creates a vulnerability window a period in which developmental timing can be disrupted by ordinary childhood stressors

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10.1186/s10020-023-00729-z 216 ZhaoW.ZhaoB.MengX.LiB.WangY.YuF.et al (2024)

correlation between COVID-19 and viral-induced ROS in lung/respiratory epithelium during this pandemic