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Description
The upregulation of JAK2, STAT3, and STAT5 facilitates oncogenesis in AML

Its main function is to regulate levels of hydrogen peroxide and peroxidation of ethanol to acetaldehyde in the presence of H2O2 (51)

It is well established that GPX4 is an attractive specific target for new pharmacological therapeutics aiming at activating cell death in cancer or inhibiting cell death in degenerative diseases

doi: 10.1271/bbb.70213

Certain phytochemicalsincluding flavonoids and tanninshave metal binding activity for cadmium, nickel, aluminum, and lead in vitro and in vivo