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Such screenings include, for example, phage display, flow cytometry, and ELISA assays to identify antigens that are efficiently expressed and have multiple epitopes and a proper folding pattern
Studies have demonstrated that germ-free animals display cecal enlargement, reduced intestinal surface area, and gastrointestinal dysregulation (11, 12)
There is some scientific evidence to support these claims
doi: 10.3389/fimmu.2023.1128301 25 LiuMLiYYuanYJiangMYinPYangD
doi: 10.3390/ijms24108728
