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The result is that it takes more to get the same effect
10.1016/j.dsx.2014.09.015 16 JiangX

A compelling body of evidence suggests that the aging process itself fosters a 'pro-ferroptotic' state in the brain, thereby lowering the threshold for neurodegeneration (101,102)

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We therefore treated astrocytes with glutamate and NH 4 Cl and examined the phosphorylation of MST1, LATS1 and YAP to observe if glutamate and NH 4 Cl can activate Hippo signaling pathway
