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Lipolytic actions of leptin are dependent on the leptin receptor, since obese fa/fa Zucker rats (112) and db/db mice (32) that have an inactivating mutation of the long form of the leptin receptor are resistant to leptin-induced lipolysis
Therefore, it is important to investigate the influence of NAM concentrations on NNMT-regulated chromatin modification in cancer cells
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doi: 10.2147/NDT.S190845
