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10.1097/00003086-199305000-00038 [DOI] [PubMed] [Google Scholar] Kawakami T., Kawai T., Takei N., Kise T., Eda S., Urist M

Neither TB-4 nor BPC-157 "stays local" both enter systemic circulation within minutes but first-pass tissue concentration is higher at the injection site before systemic dilution, which matters disproportionately for TB-4's concentration-dependent mechanism
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