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Herein, we investigated the effects of CBD on liver injury induced by chronic plus binge alcohol feeding in mice
Among them are the decrease of AKT signaling through the inhibition of the RAPTOR/mTOR complex and the interaction of GNMT with the PTEN inhibitor, PREX2
It is known that thyroid hormone can regulate hepatic metabolic pathways including cholesterol, de novo lipogenesis, fatty acid oxidation, lipophagy, and carbohydrate metabolism
Clinical trials are needed to validate antagonist efficacy and safety
