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Doctors say most patients do well on methotrexate alone, a drug thats been used for RA since the 1980s, and want to avoid the added expense and toxicity of unnecessary medications

These are exactly the kinds of changes that correlate with reduced cardiovascular risk and improved metabolic health in humans

The trials used doses ranging from 0.25 mg to 54 mg daily (well above typical protocols) for durations up to 24 weeks

Include: Doctors may recommend Vitamin B12 tablets or capsules

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