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The mesenteric arteries from murine models were pre-incubated in placental trophoblast conditioned media, which may induce endothelial dysfunction

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In addition, MC express the Mas-related G protein-coupled receptor type 2 (MRGPRX2), which can be activated by small molecules such as compound 48/80 (C48/80) or substance P (SP) and has been implicated in pseudo-allergic reactions or IgE-independent allergic reactions [11,12]

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