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There are also shifts toward pro-inflammatory metabolites, such as acetate and propionate
It is not known how Grx3 and Grx4 identify iron in yeast cells

However, S-BHB-CoA is a transient intermediate in the last round of -oxidation of fatty acids (42)

NRF2-ARE binding can regulate the expression of hundreds of cytoprotective genes including antioxidant proteins and phase II enzymes (261)

Therefore, considering the use of antioxidants to mitigate AD is an essential strategy in the management of AD
