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Annals of Thoracic Surgery 119(3):616-624, 2025

[DOI] [PubMed] [Google Scholar] 19.Paolisso G., Giugliano D., Pizza G., Gambardella A., Tesauro P., Varricchio M., DOnofrio F

Additionally, hyperglycemia has been shown to enhance the repressive histone mark H3K27me3 in human vascular endothelium through upregulation of the methyltransferase EZH2 and suppression of the demethylases UTX/JMJD3, resulting in downregulation of antioxidant genes (e.g., SOD1, SOD2) and elevated NOX4-mediated ROS production [133]

Perioperative Complication Rates Associated with Surgical Treatment (CSM) Based on a Prospective Multicenter Study of 302 Patients.CSRS, Scottsdale, Arizona, December 8-10, 2011