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Our previous results showed that colorectal cancer cells expressed GSTA4 (6) and we show in the current study that inactivation of GSTA4 in HCT116 cells decreases proliferation via inhibition of PI3K/MAPK pathways, supporting the tumor promotive role of GSTA4
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This hypothesis was directly tested in a double-blind, randomized controlled trial (RCT) by Walsh et al
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