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This includes: Those with a diagnosed B12 deficiency confirmed through blood work

[DOI] [PubMed] [Google Scholar] 47.Ventura M., Melo M., Carrilho F

J Neurosci Off J Soc Neurosci (2008) 28(35):86917

Systemic infection is among the serious hazards because live probiotic bacteria (e.g., Lactobacillus or Saccharomyces) may translocate across the gut barrier and induce septicemia, fungemia, or endocarditis
Drugs where the same dose may result in significant individual differences in blood concentration, leading to substantial pharmacokinetic variability
