5-amino-1mq nnmt inhibition mechanism – 50mg (Nicotinamide N-Methyltransferase Inhibitor) – BioPeptics 5-Amino-1MQ NNMT Inhibitor for Research
Description
Perets R
The optimal dosing, administration route, and cycling protocol for humans remain uncertain
doi: 10.1038/nm.3882
Reactions were performed with 50 M RHKKAc, a fluorogenic peptide substrate from p53 residues 379382, 500 M NAD + co-substrate, and recombinant human SIRT-1 (NAD + -dependent) enzyme
William Russell (Director, Mass Spectrometry Facility, Department of Biochemistry and Molecular Biology, UTMB) for his assistance in optimizing and running all LC/MS/MS assessments
