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Supplementation of cystine restored mTORC1 signaling and treatment with rapamycin (a specific mTORC1 inhibitor) abolished the induction, providing evidence for the direct role of mTORC1 in the phosphorylation of p70S6K (T389) and S6 (S235/236)

Nature Cancer 5(10):1515-1533, 2024
Full-length HGH191AA produces broader metabolic effects, including IGF-1 elevation and multi-system signaling, which can complicate measurement of natural hormone responsiveness

The characterization of the amino acid profile of Pleurotus ostreatus is depicted in Table 4
