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This is followed by multiple immune abnormalities: marked impairment of the immunosuppressive function of myeloid-derived suppressor cells (MDSCs), pro-inflammatory polarization of Kupffer cells, T-cell differentiation imbalance, and B-cell hyperactivation that induces antimitochondrial antibody (AMA)-mediated cytotoxicity
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3.2 The impact of radiotherapy on inducing cellular aging Radiation therapy is a cancer treatment method known for its high effectiveness and lower risk of tissue damage compared to chemotherapy [52]
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