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doi: 10.3389/fped.2018.00242 268 AppelmanBCharltonBTGouldingRPKerkhoffTJBreedveldEANoortWet al

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Overall, whilst these findings imply that increased production of ROS is associated with C9orf72-ALS, it is unclear whether loss of C9orf72 or expression of hexanucleotide repeat expansions disturbs redox homeostasis

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