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This is one of the most popular tasks in behavioral neuroscience and neuropharmacology and is sensitive to both the amnestic and memory enhancing effects of drugs, as well as gene manipulations and is dependent on intact hippocampal function.

A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation

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MRI revealed the "eye of the tiger" sign, characteristic of PKAN

Resulting cDNA was then used for qPCR using primers designed to predict M6A sites located on BDNF-AS (Supplementary Table 2)