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Reactions were performed with 0.001 mg/ml DNA substrate Poly(dI-dC), 1 M radiolabelled S-adenosyl-L-[methyl- 3 H] methionine (SAM) co-substrate, and recombinant human DNMT1 enzyme

Important considerations: AOD-9604 should be viewed as an adjunct to comprehensive lifestyle modification, not a standalone weight loss solution

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The injection bypasses the digestive system, meaning food intake does not affect its absorption or efficacy