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Piriformis Syndrome: The piriformis muscle, located deep in the buttock, spasms or tightens and irritates the sciatic nerve, which runs right beneath or sometimes through it

In alcohol-exposed rats, no change in agonist-induced GTPS binding was observed (Kufahl et al., 2011), whereas the ability of the same mGlu 2/3 agonist to reduce extracellular glutamate levels in vivo was reduced (Meinhardt et al., 2013)

Good targets