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Pathways involved in endosomal trafficking include the fusion of mature lysosomes with vesicles that contain extracellular material that has been taken up through the process of endocytosis for further digestion

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White et al., 2016

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These changes ultimately drive the development and progression of DR

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In fact, the accumulation of dysfunctional mitochondria is characteristic of aging, with decreased ATP production and increased ROS generation [10,11]

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In these cases, Dr

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