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This review examines classical pathogenic mechanisms of osteoporosisincluding estrogen deficiency, oxidative stress, and dysregulated bone metabolismand summarizes traditional botanical drugs: Astragalus polysaccharides (APS), glycyrrhizin, Cistanche deserticola polysaccharides (CDP), Eucommia ulmoides polysaccharides (EUP), and Ligustrum lucidum derivatives

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Zhang, a perennial vine in the Cucurbitaceae family, also known as Luo hanguo or monks fruit, has an important history in food and medicine (106)