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Description
We stated that to the best of our knowledge, there were no claims in the historical data used in the calculation of this adjustment for cases involving a clinical trial of a different product, and to the extent the historical data contain claims for cases involving expanded access use of immunotherapy we believe those claims would have drug charges less than $373,000

13(6 Pt 2):116S-128S

But the breakup was far from clear-cut

Stabilized STAT1 induces the production of IL-10 (an immunosuppressive cytokine), promotes the M2 polarization of macrophages, and weakens the efficacy of ICB, leading to immune resistance (132)

Targeting cancer cells using surface-modified plant-based nanoparticles: current status and future prospects
