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If nausea persists beyond 5 days post-injection or intensifies over consecutive weeks, this signals a need to pause dose escalation for an additional 24 weeks rather than pushing forward

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The American Diabetes Association (ADA) and American College of Physicians (ACP) emphasize individualized treatment approaches for glucose-lowering medications, though specific guidance on treatment interruption and resumption is limited

A total of 35 subjects were enrolled in the heavy-isotopologue challenge studies, which included either d 9 -BB or d 3 -l-carnitine

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