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Samstag Y, John I, Wabnitz GH

Ind J Clin Biochem (2026)

Those changes persist after the peptide itself has been degraded

Discovery of IPN60090, a clinical stage selective Glutaminase-1 (GLS-1) inhibitor with excellent Pharmacokinetic and physicochemical properties

392,393 Many of these substances induce widespread changes in astrocyte functions, including loss of functions and dysregulated astrogliosis, which in turn may serve as comorbidities in degenerative conditions such as AD, PD, and others
