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Various observations indicate thatvitamin B12 participates in the transfer of labile methyl groups for the formation ofmethionine, and in this way is associated with the folic acidmetabolism

Ans: When a cat's intestinal lining is damaged by conditions like inflammatory bowel disease, oral cobalamin simply does not get absorbed properly no matter how much is given

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But here's what the research says.

Many people experience symptoms of low B12 including fatigue, low mood, brain fog, and poor concentration