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Compared to chronic hGH treatment, AOD 9604 demonstrated no negative effects on insulin sensitivity

Furthermore, in MM, a subpopulation of regulatory T cells (Tregs) shows increased CD38 expression compared to T constitutive cells (Tcons), which enhances their immunosuppressive effect

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In animal studies, AOD-9604 treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity in adipose tissue