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[7] Standard oral cyanocobalamin or hydroxocobalamin tablets can be taken with or without food

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A scoping approach was selected given the anticipated heterogeneity of study designs, the predominance of preclinical literature, and the limited volume of human clinical outcome data

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So, you measure a higher B12, but part of that B12 is inactive, so useless Oral B12 supplementation, even in the form of a multivitamin preparation, may result in serum B12 concentrations just within the normal range without abolishing symptoms