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Two separate chinese articles discuss use of B12 in the period immediately after shingles and also, in a separate study, later

Differential effects of short chain fatty acids on endothelial Nlrp3 inflammasome activation and neointima formation: antioxidant action of butyrate

No matter how much B12 I took, the inflammatory signals were blocking its action at the cellular level

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects
